The International Symposium on Vasoactive Peptides is a unique forum for graduate students, post-docs, clinicians and other scientists to present and exchange new data and ideas. The first edition of the symposium was held in Ouro Preto in 1991. From the interactions started at that meeting chymase and the B1 receptor were cloned years later by Urata and Pesquero, respectively. These findings were obtained under the supervision of Professors Ganten and Bader. This fact illustrates the potential of this symposium for generating new ideas and knowledge. The XII International Symposium on Vasoactive Peptides will have as one of its main topics the recent advances on the role of the renin-angiotensin system in inflammation. The symposium will provide young scientists a venue to expand their knowledge of recent advances in the field, as well as, discuss and receive feedback on their research. The meeting is also designed to foster interactions and constructive networking with peers and established scientists.